Single-molecule analysis of CRISPR-Cas enzymes, Dr. Dina Grohman
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10. dubna 2025
14:00 – 15:00 - budova B11, místnost místnost 205
CRISPR-Cas systems constitute the adaptive immune systems of bacteria and archaea. As we scientist only discoverd CRISPR-Cas a few years ago, there is much to be learned about the diversity and function of these complex defence systems. Employing biophysical technqiues like single-molecule FRET, we seek to understand the molecular mechanisms and conformational dynamics of a subset of Cas proteins.
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